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Genetic abnormalities may cause cerebral palsy, study suggests

23:01 27-01-2012; source: www.sciencedaily.com

For years it was thought that a difficult birth and other perinatal factors were the leading causes of cerebral palsy (CP), a group of disorders that can involve brain and nervous system functions such as movement, learning, hearing, seeing and thinking. Now, researchers suggest that the majority of cerebral palsy causes may in fact be caused by genetic abnormalities.

Genetic variation that raises risk of serious complication linked to osteoporosis drugs identified

23:01 27-01-2012; source: www.sciencedaily.com

Researchers have identified a genetic variation that raises the risk of developing serious necrotic jaw bone lesions in patients who take bisphosphonates, a common class of osteoclastic inhibitors.

How cholera bacterium gains a foothold in the gut

23:01 27-01-2012; source: www.sciencedaily.com

Biologists have made an important advance in our understanding of the way cholera attacks the body. The discovery could help scientists target treatments for the globally significant intestinal disease which kills more than 100,000 people every year.

Research on vitamins could lead to the design of novel drugs to combat malaria

23:01 27-01-2012; source: www.sciencedaily.com

New research could lead to the design of more effective drugs to combat malaria. The research will enable scientists to learn more about the nature of the enzymes required for vitamin biosynthesis by the malaria causing pathogen Plasmodium. Vitamins are essential nutrients required in small amounts, the lack of which leads to deficiencies. Many pathogenic microorganisms produce vitamins, and these biosynthetic pathways may provide suitable targets for development of new drugs.

Giant cell reveals metabolic secrets

22:37 27-01-2012; source: www.sciencedaily.com

Chemical reactions within the cell produce intermediate and end products in the form of small molecules called metabolites. Using an approach called metabolomics, researchers have elucidated the localization and dynamics of 125 metabolites within a single giant cell of the freshwater alga Chara australis1. The team's findings provide important insights into the fundamental processes of cells in general.

How cholera bacterium gains a foothold in the gut

22:37 27-01-2012; source: www.sciencedaily.com

Biologists have made an important advance in our understanding of the way cholera attacks the body. The discovery could help scientists target treatments for the globally significant intestinal disease which kills more than 100,000 people every year.

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